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Treating fragile X syndrome with a new molecular strategy

Caption:Observations of the small protrusions that line the dendrites of neurons, called spines, provided a critical readout of the function of the cells' NMDA receptors in the new study, as well as in a precursor to the research back in 2020. This is a two-photon microscope image, which is approaching the limits of optical imaging (hence its blurriness). Credits:Image: Stepanie Barnes/MIT Bear Lab

Fragile X syndrome is the most common genetically-caused autism spectrum disorder. It causes a range of developmental issues, including intellectual disabilities and behavioral challenges. Based on more than two decades of research, MIT neuroscientists at The Picower Institute for Learning and Memory have developed a new way to treat the pathology and symptoms of fragile […]

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